产品货号：
Z21044
中文名称：
MRP5/ABCC5抗体
英文名称：
Anti-MRP5/ABCC5 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MRP5/ABCC5 Antibody |
| 指标别名 | ABC33;ABCC5;MOAT C;MOATC;MRP5;pABC11;SMRP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ELISA |
| 基因名称 | ABCC5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human MRP5 protein. |
| 计算分子量 | 161KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | MRP5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Multidrug resistance-associated protein 5 is a protein that in humans is encoded by the ABCC5 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.This protein functions in the cellular export of its substrate,cyclic nucleotides.This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides.Studies show that this protein provides resistance to thiopurine anticancer drugs,6-mercatopurine and thioguanine,and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | O15440 |
| 基因名全称 | Multidrug resistance-associated protein 5 |
| 蛋白名全称 | Multidrug resistance-associated protein 5 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
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